Longitudinal.Rmd
This package vignette demonstrates how to use the ADNIMERGE package to simple longitudinal summaries and plots with R and knitr.
Report generated from Enrollment.Rmd
options(digits = 3)
library(knitr)
library(ADNIMERGE)
library(ggplot2)
library(Hmisc)
library(gridExtra)
library(RColorBrewer)
library(patchwork)
library(tidyverse)
library(kableExtra)
source("https://adni.bitbucket.io/myfunctions.R")
theme_set(theme_bw())
c("#2b8cbe", "#fc8d59", "#e34a33")
dx3pal <- function(...) scale_colour_manual(..., values = dx3pal)
scale_colour_discrete <- function(...) scale_fill_manual(..., values = dx3pal) scale_fill_discrete <-
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 490 | -13.00 | 0 | 0.00e+00 | -0.191 | 11.67 |
12 | 472 | -12.33 | 0 | -3.40e-01 | -0.497 | 12.67 |
24 | 564 | -10.33 | 0 | 0.00e+00 | -0.131 | 15.67 |
30 | 28 | -5.67 | 0 | 3.30e-01 | 0.488 | 7.00 |
36 | 242 | -11.34 | 0 | 0.00e+00 | 0.167 | 26.00 |
42 | 8 | -6.67 | 0 | 1.33e+00 | 0.624 | 7.00 |
48 | 317 | -8.00 | 0 | 3.30e-01 | 0.862 | 28.67 |
54 | 24 | -8.33 | 0 | 6.70e-01 | 0.182 | 8.00 |
60 | 136 | -7.67 | 0 | 6.70e-01 | 1.534 | 22.67 |
66 | 51 | -5.67 | 0 | -6.70e-01 | -0.223 | 9.00 |
72 | 177 | -7.00 | 0 | 1.00e+00 | 2.162 | 33.67 |
78 | 43 | -6.33 | 0 | 1.00e+00 | 1.170 | 14.67 |
84 | 118 | -8.67 | 0 | 1.67e+00 | 3.365 | 27.33 |
90 | 38 | -6.67 | 0 | 1.67e+00 | 1.518 | 11.00 |
96 | 109 | -9.33 | 0 | 3.00e+00 | 4.315 | 42.67 |
102 | 20 | -3.67 | 0 | 2.00e+00 | 2.333 | 8.33 |
108 | 67 | -5.33 | 0 | 3.33e+00 | 6.901 | 70.67 |
114 | 12 | -5.00 | 0 | 0.00e+00 | 1.639 | 19.00 |
120 | 63 | -6.00 | 0 | 3.00e+00 | 5.243 | 43.67 |
126 | 11 | -2.33 | 0 | 3.67e+00 | 3.880 | 13.67 |
132 | 27 | -3.34 | 0 | 3.33e+00 | 5.284 | 28.67 |
138 | 9 | -9.34 | 0 | 8.66e+00 | 12.702 | 44.67 |
144 | 22 | -3.67 | 0 | 5.00e+00 | 6.787 | 24.67 |
150 | 9 | -6.33 | 0 | 7.33e+00 | 13.852 | 61.34 |
156 | 22 | -2.00 | 0 | 4.00e+00 | 6.758 | 26.33 |
162 | 9 | -2.67 | 0 | 5.33e+00 | 14.666 | 53.00 |
168 | 5 | -4.34 | 0 | 2.33e+00 | 1.332 | 6.00 |
180 | 13 | -2.00 | 0 | 2.33e+00 | 4.204 | 26.00 |
Dementia | ||||||
6 | 800 | -15.33 | 0 | 0.00e+00 | 0.493 | 17.66 |
12 | 899 | -15.00 | 0 | 3.30e-01 | 0.714 | 54.00 |
18 | 325 | -14.00 | 0 | 2.67e+00 | 2.976 | 28.33 |
24 | 722 | -12.00 | 0 | 1.67e+00 | 2.331 | 42.33 |
30 | 11 | -4.00 | 0 | 6.00e+00 | 6.122 | 20.00 |
36 | 597 | -14.00 | 0 | 2.00e+00 | 3.634 | 49.00 |
MCI | ||||||
42 | 5 | -8.00 | 0 | -1.33e+00 | -0.400 | 6.67 |
48 | 401 | -14.33 | 0 | 3.00e+00 | 4.919 | 55.00 |
54 | 6 | -3.67 | 0 | 2.67e+00 | 5.055 | 16.67 |
60 | 239 | -14.33 | 0 | 3.67e+00 | 6.679 | 71.00 |
66 | 31 | -8.00 | 0 | 1.33e+00 | 4.044 | 30.00 |
72 | 173 | -17.33 | 0 | 4.33e+00 | 6.909 | 61.33 |
78 | 37 | -7.00 | 0 | 3.30e-01 | 2.792 | 38.67 |
84 | 131 | -11.67 | 0 | 4.00e+00 | 6.840 | 53.67 |
90 | 41 | -7.67 | 0 | 2.00e+00 | 2.521 | 20.00 |
96 | 94 | -11.00 | 0 | 4.00e+00 | 7.592 | 59.00 |
102 | 33 | -8.00 | 0 | 1.33e+00 | 1.838 | 21.00 |
108 | 61 | -10.67 | 0 | 6.70e-01 | 4.781 | 28.33 |
114 | 21 | -7.33 | 0 | 3.30e-01 | 1.270 | 14.00 |
120 | 42 | -10.00 | 0 | 2.33e+00 | 5.754 | 38.67 |
126 | 16 | -10.67 | 0 | 8.88e-16 | 3.458 | 27.00 |
132 | 17 | -6.00 | 0 | 3.00e+00 | 5.117 | 28.67 |
138 | 12 | -10.33 | 0 | 5.33e+00 | 8.138 | 21.67 |
144 | 7 | -4.66 | 0 | 3.67e+00 | 8.050 | 39.67 |
150 | 8 | -12.33 | 0 | -1.65e-01 | 1.834 | 22.67 |
6 | 298 | -12.00 | 0 | 2.34e+00 | 2.501 | 23.00 |
12 | 294 | -13.00 | 0 | 3.67e+00 | 4.895 | 31.00 |
18 | 6 | -4.67 | 0 | 2.16e+00 | 11.055 | 45.67 |
24 | 170 | -5.67 | 0 | 8.00e+00 | 10.195 | 37.00 |
30 | 5 | -1.67 | 0 | 5.67e+00 | 6.602 | 12.67 |
36 | 11 | 3.67 | 0 | 9.34e+00 | 13.910 | 35.33 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 494 | -5 | 0 | 0.0 | -0.0729 | 4 |
12 | 478 | -8 | 0 | 0.0 | -0.1109 | 4 |
24 | 573 | -24 | 0 | 0.0 | -0.1658 | 4 |
30 | 29 | -3 | 0 | 0.0 | -0.2069 | 2 |
36 | 248 | -9 | 0 | 0.0 | -0.2500 | 4 |
42 | 8 | 0 | 0 | 0.0 | 0.5000 | 2 |
48 | 320 | -14 | 0 | 0.0 | -0.3000 | 4 |
54 | 23 | -2 | 0 | 0.0 | 0.1739 | 3 |
60 | 137 | -10 | 0 | 0.0 | -0.2993 | 5 |
66 | 51 | -6 | 0 | 0.0 | -0.2157 | 4 |
72 | 175 | -8 | 0 | 0.0 | -0.4000 | 5 |
78 | 43 | -8 | 0 | 0.0 | -0.5116 | 3 |
84 | 118 | -12 | 0 | 0.0 | -0.8983 | 3 |
90 | 39 | -4 | 0 | 0.0 | -0.5897 | 4 |
96 | 109 | -18 | 0 | 0.0 | -1.1284 | 4 |
102 | 21 | -5 | 0 | 0.0 | -0.4762 | 3 |
108 | 67 | -17 | 0 | 0.0 | -1.6866 | 5 |
114 | 13 | -11 | 0 | -1.0 | -1.6923 | 1 |
120 | 61 | -21 | 0 | -1.0 | -1.5902 | 3 |
126 | 11 | -4 | 0 | -1.0 | -0.8182 | 1 |
132 | 28 | -5 | 0 | -1.0 | -0.7143 | 4 |
138 | 10 | -17 | 0 | -2.0 | -5.3000 | 0 |
144 | 22 | -9 | 0 | -1.0 | -1.4091 | 3 |
150 | 10 | -23 | 0 | -1.0 | -6.5000 | 1 |
156 | 23 | -9 | 0 | 0.0 | -0.7826 | 3 |
162 | 9 | -18 | 0 | 0.0 | -4.3333 | 1 |
168 | 5 | 0 | 0 | 0.0 | 0.6000 | 2 |
180 | 13 | -6 | 0 | -1.0 | -1.1538 | 2 |
Dementia | ||||||
6 | 808 | -10 | 0 | 0.0 | -0.5087 | 5 |
12 | 907 | -12 | 0 | 0.0 | -0.5788 | 6 |
18 | 329 | -15 | 0 | -1.0 | -1.1824 | 5 |
24 | 736 | -19 | 0 | -1.0 | -1.2418 | 6 |
30 | 10 | -7 | 0 | -2.5 | -2.8000 | 3 |
36 | 609 | -23 | 0 | -1.0 | -1.7816 | 6 |
MCI | ||||||
48 | 407 | -20 | 0 | -1.0 | -2.2703 | 5 |
54 | 6 | -5 | 0 | -3.0 | -2.5000 | 1 |
60 | 243 | -30 | 0 | -1.0 | -2.8107 | 5 |
66 | 34 | -15 | 0 | -1.0 | -2.3824 | 4 |
72 | 174 | -25 | 0 | -2.0 | -3.3563 | 5 |
78 | 40 | -16 | 0 | -1.0 | -1.5750 | 4 |
84 | 135 | -24 | 0 | -1.0 | -2.7333 | 5 |
90 | 44 | -20 | 0 | -0.5 | -1.9773 | 6 |
96 | 97 | -21 | 0 | -1.0 | -3.2784 | 4 |
102 | 34 | -9 | 0 | -1.0 | -0.9412 | 5 |
108 | 66 | -20 | 0 | -1.0 | -2.9242 | 3 |
114 | 21 | -4 | 0 | -1.0 | -1.0476 | 4 |
120 | 43 | -16 | 0 | 0.0 | -2.0000 | 3 |
126 | 16 | -9 | 0 | -1.0 | -1.9375 | 2 |
132 | 18 | -13 | 0 | -0.5 | -2.3333 | 2 |
138 | 12 | -11 | 0 | -2.5 | -2.9167 | 7 |
144 | 7 | -16 | 0 | 0.0 | -4.1429 | 1 |
150 | 8 | -10 | 0 | 0.5 | -0.3750 | 3 |
6 | 312 | -16 | 0 | -1.0 | -1.1410 | 8 |
12 | 306 | -18 | 0 | -2.0 | -2.3529 | 5 |
18 | 7 | -19 | 0 | -3.0 | -7.2857 | 0 |
24 | 187 | -22 | 0 | -3.0 | -4.4545 | 5 |
30 | 5 | -8 | 0 | -2.0 | -2.4000 | 2 |
36 | 13 | -22 | 0 | -5.0 | -8.0769 | 1 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 490 | -1.0 | 0 | 0.00 | 0.0745 | 4.0 |
12 | 472 | -1.0 | 0 | 0.00 | 0.1006 | 4.0 |
24 | 591 | -1.0 | 0 | 0.00 | 0.1497 | 5.0 |
30 | 31 | -0.5 | 0 | 0.00 | 0.2258 | 3.5 |
36 | 240 | -0.5 | 0 | 0.00 | 0.2896 | 6.0 |
42 | 9 | 0.0 | 0 | 0.00 | 0.0000 | 0.0 |
48 | 316 | -0.5 | 0 | 0.00 | 0.2563 | 5.5 |
54 | 22 | -0.5 | 0 | 0.00 | 0.1591 | 1.5 |
60 | 143 | -0.5 | 0 | 0.00 | 0.4301 | 11.0 |
66 | 54 | -0.5 | 0 | 0.00 | 0.4352 | 5.5 |
72 | 180 | -0.5 | 0 | 0.00 | 0.4722 | 7.0 |
78 | 50 | -0.5 | 0 | 0.00 | 0.6200 | 10.0 |
84 | 128 | -0.5 | 0 | 0.00 | 0.8789 | 16.0 |
90 | 42 | 0.0 | 0 | 0.00 | 0.7143 | 12.0 |
96 | 115 | -0.5 | 0 | 0.00 | 1.0652 | 13.0 |
102 | 31 | 0.0 | 0 | 0.00 | 1.0000 | 15.5 |
108 | 74 | 0.0 | 0 | 0.50 | 1.8243 | 18.0 |
114 | 17 | 0.0 | 0 | 0.00 | 1.0882 | 9.0 |
120 | 64 | 0.0 | 0 | 0.00 | 1.4844 | 17.5 |
126 | 12 | 0.0 | 0 | 0.25 | 0.7083 | 3.0 |
132 | 30 | 0.0 | 0 | 0.00 | 0.5833 | 6.0 |
138 | 12 | 0.0 | 0 | 1.00 | 4.5000 | 17.0 |
144 | 23 | 0.0 | 0 | 0.00 | 1.2826 | 8.0 |
150 | 12 | 0.0 | 0 | 1.00 | 4.8333 | 15.0 |
156 | 24 | 0.0 | 0 | 0.25 | 1.2708 | 7.0 |
162 | 10 | 0.0 | 0 | 0.75 | 6.8500 | 18.0 |
168 | 9 | 0.0 | 0 | 0.50 | 1.5000 | 8.0 |
180 | 15 | 0.0 | 0 | 0.00 | 1.1000 | 11.0 |
186 | 6 | 0.0 | 0 | 0.00 | 0.4167 | 2.5 |
Dementia | ||||||
6 | 804 | -3.5 | 0 | 0.00 | 0.2363 | 8.0 |
12 | 907 | -3.0 | 0 | 0.00 | 0.3699 | 8.0 |
18 | 329 | -2.0 | 0 | 0.50 | 0.9726 | 9.0 |
24 | 748 | -3.0 | 0 | 0.50 | 0.9305 | 11.5 |
30 | 12 | -0.5 | 0 | 0.00 | 0.6250 | 3.0 |
36 | 617 | -3.5 | 0 | 0.50 | 1.3476 | 12.5 |
MCI | ||||||
42 | 5 | -1.0 | 0 | -0.50 | -0.3000 | 1.0 |
48 | 412 | -3.5 | 0 | 0.50 | 1.7112 | 16.0 |
54 | 6 | -1.0 | 0 | 1.25 | 1.0000 | 2.5 |
60 | 254 | -3.0 | 0 | 1.00 | 2.2992 | 16.0 |
66 | 36 | -3.0 | 0 | 0.50 | 1.9861 | 15.0 |
72 | 187 | -3.0 | 0 | 1.50 | 2.9652 | 16.0 |
78 | 42 | -2.0 | 0 | 0.00 | 1.5357 | 15.5 |
84 | 150 | -3.0 | 0 | 1.00 | 3.0067 | 17.0 |
90 | 45 | -3.5 | 0 | 0.00 | 0.6889 | 12.5 |
96 | 117 | -2.5 | 0 | 1.00 | 3.0128 | 16.0 |
102 | 37 | -3.5 | 0 | -0.50 | 0.4189 | 9.5 |
108 | 86 | -2.5 | 0 | 1.00 | 3.2093 | 16.5 |
114 | 22 | -1.0 | 0 | -0.25 | 1.2500 | 14.5 |
120 | 55 | -1.5 | 0 | 0.00 | 1.9636 | 16.5 |
126 | 17 | -1.0 | 0 | 0.00 | 1.7059 | 15.0 |
132 | 22 | -2.5 | 0 | 0.75 | 2.4545 | 17.0 |
138 | 13 | -1.5 | 0 | 1.00 | 2.4231 | 9.5 |
144 | 10 | -1.0 | 0 | 6.00 | 7.2000 | 16.5 |
150 | 10 | -1.5 | 0 | -0.50 | 0.9500 | 8.5 |
6 | 311 | -3.0 | 0 | 0.50 | 0.7974 | 9.0 |
12 | 313 | -3.0 | 0 | 1.00 | 1.7364 | 11.5 |
18 | 8 | -0.5 | 0 | 3.00 | 4.1250 | 13.0 |
24 | 190 | -3.0 | 0 | 3.00 | 3.4184 | 14.0 |
30 | 5 | 0.5 | 0 | 2.00 | 3.4000 | 11.5 |
36 | 14 | -0.5 | 0 | 6.50 | 6.0714 | 12.0 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 273 | -1.500 | 0 | 0.000 | 0.03031 | 1.625 |
12 | 269 | -1.375 | 0 | 0.000 | 0.01965 | 1.625 |
24 | 402 | -2.000 | 0 | 0.000 | 0.02230 | 1.750 |
30 | 33 | -0.750 | 0 | -0.125 | -0.10606 | 0.625 |
36 | 61 | -0.589 | 0 | 0.000 | 0.03132 | 1.250 |
42 | 9 | -0.875 | 0 | -0.125 | -0.27116 | 0.000 |
48 | 202 | -1.375 | 0 | 0.000 | 0.04500 | 2.125 |
54 | 25 | -1.429 | 0 | 0.125 | 0.20643 | 1.375 |
60 | 31 | -1.000 | 0 | 0.125 | 0.14343 | 1.000 |
66 | 54 | -1.000 | 0 | 0.107 | 0.12566 | 1.250 |
72 | 63 | -0.750 | 0 | 0.125 | 0.16808 | 1.625 |
78 | 50 | -1.321 | 0 | 0.107 | 0.14405 | 1.625 |
84 | 26 | -1.500 | 0 | 0.250 | 0.18521 | 1.821 |
90 | 42 | -0.714 | 0 | 0.000 | 0.11480 | 1.500 |
96 | 44 | -1.125 | 0 | 0.188 | 0.26502 | 1.857 |
102 | 30 | -0.750 | 0 | 0.125 | 0.29167 | 2.250 |
108 | 12 | -0.375 | 0 | 0.125 | 0.31250 | 1.250 |
114 | 16 | -0.375 | 0 | 0.125 | 0.17076 | 1.375 |
120 | 17 | -1.125 | 0 | 0.125 | 0.07353 | 0.875 |
126 | 10 | -0.625 | 0 | 0.188 | 0.34821 | 1.500 |
Dementia | ||||||
6 | 428 | -2.125 | 0 | -0.125 | -0.10402 | 1.625 |
12 | 555 | -2.250 | 0 | 0.000 | -0.05281 | 1.750 |
18 | 8 | -1.250 | 0 | -0.214 | -0.16295 | 0.875 |
MCI | ||||||
24 | 449 | -2.875 | 0 | 0.000 | -0.03188 | 2.500 |
30 | 12 | -0.750 | 0 | 0.250 | 0.32738 | 1.250 |
36 | 360 | -2.375 | 0 | 0.000 | -0.02789 | 2.500 |
42 | 5 | -1.375 | 0 | -0.625 | -0.22500 | 1.500 |
48 | 257 | -2.500 | 0 | -0.125 | -0.09913 | 2.357 |
54 | 6 | -0.661 | 0 | -0.188 | -0.19345 | 0.125 |
60 | 124 | -1.500 | 0 | 0.000 | 0.00974 | 1.375 |
66 | 33 | -1.250 | 0 | -0.125 | -0.02183 | 1.750 |
72 | 66 | -1.750 | 0 | 0.000 | 0.07359 | 1.750 |
78 | 38 | -2.125 | 0 | -0.125 | -0.02538 | 2.000 |
84 | 56 | -2.375 | 0 | -0.125 | -0.07058 | 1.625 |
90 | 45 | -1.375 | 0 | -0.125 | -0.05317 | 2.214 |
96 | 41 | -2.500 | 0 | -0.250 | -0.18902 | 1.625 |
102 | 36 | -2.250 | 0 | -0.125 | -0.22173 | 1.250 |
108 | 33 | -2.250 | 0 | -0.125 | -0.08081 | 1.875 |
114 | 23 | -1.375 | 0 | 0.000 | 0.14130 | 1.375 |
120 | 27 | -1.875 | 0 | 0.000 | -0.00265 | 1.625 |
126 | 12 | -1.250 | 0 | -0.312 | -0.01190 | 1.375 |
132 | 11 | -1.500 | 0 | -0.375 | -0.36526 | 1.625 |
6 | 124 | -1.875 | 0 | 0.000 | -0.05921 | 1.750 |
12 | 131 | -2.000 | 0 | 0.000 | -0.12325 | 2.000 |
24 | 41 | -1.750 | 0 | -0.125 | -0.10192 | 2.125 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 263 | -1.375 | 0 | 0.0000 | 0.01722 | 1.625 |
12 | 263 | -1.500 | 0 | 0.0000 | 0.03849 | 2.125 |
24 | 385 | -1.500 | 0 | 0.0000 | 0.04771 | 2.125 |
30 | 31 | -0.375 | 0 | 0.0000 | 0.12154 | 2.125 |
36 | 57 | -1.375 | 0 | 0.0000 | 0.12901 | 2.125 |
42 | 9 | -0.714 | 0 | 0.0000 | -0.03175 | 0.429 |
48 | 193 | -1.250 | 0 | 0.0000 | 0.10848 | 2.500 |
54 | 24 | -0.500 | 0 | 0.0625 | 0.16295 | 1.042 |
60 | 30 | -0.750 | 0 | 0.0000 | 0.18770 | 2.464 |
66 | 52 | -0.625 | 0 | 0.1250 | 0.18681 | 1.500 |
72 | 62 | -1.500 | 0 | 0.0000 | 0.23032 | 2.250 |
78 | 52 | -2.375 | 0 | 0.1250 | 0.16854 | 2.750 |
84 | 26 | -0.750 | 0 | 0.0000 | 0.30288 | 2.750 |
90 | 41 | -0.589 | 0 | 0.1250 | 0.31794 | 2.250 |
96 | 40 | -1.375 | 0 | 0.0000 | 0.23631 | 3.000 |
102 | 27 | -0.500 | 0 | 0.0000 | 0.42593 | 3.000 |
108 | 13 | -0.375 | 0 | 0.1250 | 0.55769 | 2.750 |
114 | 16 | -0.500 | 0 | 0.2500 | 0.59821 | 2.750 |
120 | 15 | -0.625 | 0 | 0.0000 | 0.20238 | 2.125 |
126 | 9 | -0.125 | 0 | 0.8750 | 0.74537 | 1.750 |
Dementia | ||||||
6 | 424 | -1.875 | 0 | 0.0000 | 0.00345 | 2.125 |
12 | 549 | -2.750 | 0 | 0.0000 | 0.01808 | 2.250 |
18 | 8 | -1.750 | 0 | -0.0714 | -0.28348 | 0.250 |
24 | 449 | -1.875 | 0 | 0.0000 | 0.09842 | 2.125 |
MCI | ||||||
30 | 12 | -1.750 | 0 | 0.0625 | 0.19792 | 2.125 |
36 | 357 | -2.250 | 0 | 0.1250 | 0.15905 | 2.143 |
42 | 5 | -0.625 | 0 | 0.0476 | -0.06905 | 0.357 |
48 | 252 | -1.750 | 0 | 0.1250 | 0.20394 | 2.875 |
54 | 6 | -0.125 | 0 | 0.5000 | 0.58333 | 1.625 |
60 | 120 | -1.625 | 0 | 0.1250 | 0.26644 | 2.500 |
66 | 37 | -0.875 | 0 | 0.1250 | 0.24356 | 1.625 |
72 | 64 | -1.625 | 0 | 0.1250 | 0.24881 | 2.286 |
78 | 43 | -1.125 | 0 | 0.0000 | 0.09983 | 2.000 |
84 | 58 | -1.125 | 0 | 0.1250 | 0.38378 | 2.500 |
90 | 46 | -1.250 | 0 | 0.0000 | 0.10688 | 2.167 |
96 | 41 | -1.250 | 0 | 0.3750 | 0.37398 | 2.375 |
102 | 35 | -2.000 | 0 | 0.0000 | 0.07449 | 2.000 |
108 | 36 | -0.625 | 0 | 0.1250 | 0.35417 | 2.500 |
114 | 23 | -0.875 | 0 | 0.0000 | 0.19658 | 1.643 |
120 | 26 | -0.500 | 0 | 0.0000 | 0.21360 | 1.500 |
126 | 11 | -1.125 | 0 | 0.6250 | 0.28409 | 1.750 |
132 | 11 | -1.125 | 0 | -0.0536 | 0.30519 | 2.500 |
6 | 130 | -2.750 | 0 | 0.0000 | 0.04211 | 1.625 |
12 | 151 | -1.000 | 0 | 0.1250 | 0.23266 | 2.125 |
24 | 54 | -1.750 | 0 | 0.1250 | 0.18022 | 1.750 |
30 | 5 | 0.000 | 0 | 0.2500 | 0.55000 | 1.250 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 273 | -1.139 | 0 | 0.00000 | 1.78e-02 | 0.821 |
12 | 269 | -0.751 | 0 | 0.00000 | 2.71e-02 | 1.462 |
24 | 402 | -1.342 | 0 | 0.00000 | 2.11e-02 | 1.179 |
30 | 33 | -0.658 | 0 | -0.07895 | -9.09e-02 | 0.421 |
36 | 61 | -0.526 | 0 | 0.00000 | 6.71e-02 | 1.237 |
42 | 9 | -0.658 | 0 | -0.04386 | -1.52e-01 | 0.184 |
48 | 203 | -0.985 | 0 | 0.02564 | 5.35e-02 | 1.718 |
54 | 25 | -0.695 | 0 | 0.10526 | 1.18e-01 | 0.824 |
60 | 31 | -0.725 | 0 | 0.13158 | 1.05e-01 | 0.694 |
66 | 54 | -0.354 | 0 | 0.09582 | 1.47e-01 | 0.930 |
72 | 63 | -1.006 | 0 | 0.10661 | 9.23e-02 | 1.030 |
78 | 50 | -0.575 | 0 | 0.06078 | 1.15e-01 | 1.300 |
84 | 26 | -0.784 | 0 | 0.15605 | 1.29e-01 | 1.053 |
90 | 42 | -0.421 | 0 | 0.08401 | 1.58e-01 | 1.164 |
96 | 44 | -1.111 | 0 | 0.11167 | 1.42e-01 | 1.105 |
102 | 30 | -0.616 | 0 | 0.10819 | 3.25e-01 | 2.641 |
108 | 12 | -0.271 | 0 | 0.17645 | 1.86e-01 | 0.621 |
114 | 16 | -0.220 | 0 | 0.08820 | 1.92e-01 | 0.830 |
120 | 17 | -1.164 | 0 | 0.05398 | 3.65e-02 | 0.537 |
126 | 10 | -0.123 | 0 | 0.09709 | 2.59e-01 | 0.891 |
Dementia | ||||||
6 | 430 | -2.083 | 0 | -0.02632 | -3.50e-02 | 1.590 |
12 | 558 | -1.692 | 0 | -0.02257 | -2.03e-02 | 1.667 |
18 | 8 | -0.737 | 0 | 0.09211 | 6.96e-03 | 0.447 |
MCI | ||||||
24 | 451 | -1.688 | 0 | 0.00000 | 2.73e-02 | 1.735 |
30 | 12 | -0.500 | 0 | 0.14314 | 1.63e-01 | 0.763 |
36 | 356 | -1.734 | 0 | 0.02564 | 4.88e-02 | 1.989 |
42 | 5 | -0.658 | 0 | -0.04934 | 1.23e-01 | 1.486 |
48 | 256 | -2.308 | 0 | 0.02564 | 3.24e-02 | 2.708 |
54 | 6 | -0.333 | 0 | 0.11100 | 1.80e-01 | 0.940 |
60 | 123 | -1.215 | 0 | 0.02564 | 6.30e-02 | 1.133 |
66 | 32 | -1.094 | 0 | -0.01008 | 7.28e-02 | 1.478 |
72 | 66 | -0.971 | 0 | 0.09419 | 9.12e-02 | 0.878 |
78 | 38 | -1.125 | 0 | -0.01251 | 4.18e-02 | 1.596 |
84 | 56 | -1.065 | 0 | 0.00742 | 3.03e-02 | 1.383 |
90 | 45 | -1.094 | 0 | 0.02853 | 7.00e-02 | 2.589 |
96 | 41 | -1.094 | 0 | -0.10121 | -3.12e-03 | 1.409 |
102 | 36 | -0.874 | 0 | 0.05115 | -4.09e-02 | 0.615 |
108 | 33 | -0.862 | 0 | 0.00925 | 5.88e-02 | 1.473 |
114 | 23 | -0.884 | 0 | 0.18016 | 2.03e-01 | 1.112 |
120 | 27 | -1.365 | 0 | 0.04184 | 4.33e-02 | 1.383 |
126 | 12 | -1.474 | 0 | 0.16664 | 1.21e-01 | 1.358 |
132 | 11 | -1.392 | 0 | -0.29150 | -3.18e-01 | 0.830 |
6 | 120 | -1.692 | 0 | 0.02315 | -1.19e-02 | 1.513 |
12 | 129 | -1.380 | 0 | -0.00962 | 9.59e-05 | 2.098 |
24 | 41 | -1.431 | 0 | 0.05714 | 1.06e-01 | 2.321 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
6 | 265 | -0.8794 | 0 | 0.00000 | 0.00909 | 0.846 |
12 | 263 | -1.2051 | 0 | 0.00000 | 0.03792 | 1.615 |
24 | 385 | -1.1255 | 0 | 0.00000 | 0.04239 | 2.000 |
30 | 31 | -0.3158 | 0 | 0.00284 | 0.04355 | 1.113 |
36 | 57 | -1.3300 | 0 | 0.05128 | 0.13448 | 2.051 |
42 | 9 | -0.4324 | 0 | 0.00000 | 0.04505 | 0.237 |
48 | 194 | -1.0513 | 0 | 0.00000 | 0.08174 | 2.289 |
54 | 24 | -0.3183 | 0 | 0.07292 | 0.15518 | 0.847 |
60 | 30 | -0.5405 | 0 | 0.03975 | 0.20949 | 2.538 |
66 | 52 | -0.5641 | 0 | 0.03121 | 0.13301 | 1.426 |
72 | 61 | -0.9939 | 0 | 0.05263 | 0.18249 | 2.520 |
78 | 52 | -1.5441 | 0 | 0.05263 | 0.19780 | 2.947 |
84 | 26 | -0.6457 | 0 | 0.00607 | 0.27654 | 2.397 |
90 | 41 | -0.5641 | 0 | 0.09048 | 0.22968 | 2.305 |
96 | 41 | -0.9939 | 0 | 0.00000 | 0.17574 | 2.474 |
102 | 27 | -0.1433 | 0 | 0.08165 | 0.33247 | 2.447 |
108 | 13 | -0.1102 | 0 | 0.26721 | 0.43386 | 2.872 |
114 | 16 | -0.5641 | 0 | 0.15688 | 0.45668 | 2.735 |
120 | 15 | -0.4595 | 0 | 0.00000 | 0.04161 | 0.727 |
126 | 9 | -0.0294 | 0 | 0.70672 | 0.54997 | 1.158 |
Dementia | ||||||
6 | 426 | -1.4615 | 0 | 0.02065 | 0.05147 | 1.991 |
12 | 549 | -2.0388 | 0 | 0.05128 | 0.08818 | 2.224 |
18 | 8 | -0.5789 | 0 | -0.00213 | -0.01280 | 0.500 |
24 | 450 | -1.4103 | 0 | 0.11034 | 0.18574 | 2.410 |
MCI | ||||||
30 | 12 | -0.9211 | 0 | 0.28363 | 0.32844 | 1.586 |
36 | 356 | -2.1375 | 0 | 0.15385 | 0.25792 | 2.513 |
42 | 5 | -0.0931 | 0 | 0.10526 | 0.10284 | 0.395 |
48 | 252 | -2.1147 | 0 | 0.14523 | 0.27626 | 2.615 |
54 | 6 | -0.1005 | 0 | 0.42689 | 0.52356 | 1.318 |
60 | 120 | -1.0538 | 0 | 0.17486 | 0.30872 | 2.401 |
66 | 37 | -0.6606 | 0 | 0.22637 | 0.40747 | 1.912 |
72 | 64 | -1.1026 | 0 | 0.13839 | 0.22995 | 1.830 |
78 | 43 | -1.0155 | 0 | 0.13158 | 0.29339 | 2.250 |
84 | 58 | -1.3448 | 0 | 0.16599 | 0.43692 | 2.300 |
90 | 46 | -0.9946 | 0 | 0.14782 | 0.30064 | 2.400 |
96 | 41 | -1.0816 | 0 | 0.12233 | 0.47064 | 2.299 |
102 | 35 | -1.2051 | 0 | 0.22973 | 0.29869 | 2.513 |
108 | 36 | -0.5886 | 0 | 0.08536 | 0.45693 | 2.819 |
114 | 23 | -0.4352 | 0 | 0.16667 | 0.32680 | 1.556 |
120 | 26 | -0.2598 | 0 | 0.02932 | 0.19987 | 1.998 |
126 | 11 | -0.1988 | 0 | 0.05331 | 0.43431 | 1.517 |
132 | 11 | -0.5641 | 0 | 0.00000 | 0.26217 | 1.173 |
6 | 130 | -2.5000 | 0 | 0.12557 | 0.10533 | 1.333 |
12 | 152 | -1.4615 | 0 | 0.32895 | 0.34423 | 1.571 |
24 | 54 | -0.6494 | 0 | 0.45338 | 0.46613 | 2.079 |
30 | 5 | 0.5789 | 0 | 0.80105 | 0.82319 | 1.105 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
3 | 182 | -815 | 0 | -18.5 | -15.7 | 756.0 |
6 | 329 | -1940 | 0 | -30.0 | -54.4 | 758.0 |
12 | 385 | -1965 | 0 | -66.2 | -94.5 | 774.0 |
24 | 434 | -1435 | 0 | -167.4 | -184.7 | 2590.0 |
30 | 22 | -638 | 0 | -229.9 | -246.6 | 90.9 |
36 | 139 | -1117 | 0 | -245.0 | -260.2 | 622.0 |
48 | 200 | -3084 | 0 | -349.0 | -415.1 | 744.0 |
54 | 12 | -662 | 0 | -280.2 | -291.7 | -41.9 |
60 | 79 | -1269 | 0 | -412.0 | -399.5 | 655.0 |
66 | 33 | -1160 | 0 | -450.2 | -482.0 | 265.2 |
72 | 113 | -1820 | 0 | -485.0 | -515.2 | 395.5 |
78 | 27 | -1327 | 0 | -495.7 | -560.1 | 158.2 |
84 | 29 | -2842 | 0 | -435.0 | -596.4 | 148.0 |
90 | 24 | -1598 | 0 | -635.4 | -709.0 | 133.0 |
96 | 41 | -2052 | 0 | -609.3 | -684.8 | 100.6 |
102 | 9 | -946 | 0 | -611.6 | -564.9 | -230.6 |
108 | 17 | -1842 | 0 | -490.0 | -687.7 | 209.0 |
120 | 17 | -2142 | 0 | -814.7 | -924.8 | -172.5 |
132 | 17 | -1585 | 0 | -788.6 | -675.7 | 532.4 |
138 | 6 | -1218 | 0 | -733.9 | -688.3 | -288.9 |
144 | 12 | -1535 | 0 | -669.2 | -660.1 | 310.6 |
156 | 12 | -1367 | 0 | -938.1 | -917.3 | -231.9 |
Dementia | ||||||
3 | 354 | -801 | 0 | -34.0 | -30.0 | 885.0 |
6 | 600 | -1376 | 0 | -77.5 | -68.7 | 733.0 |
12 | 641 | -969 | 0 | -152.0 | -157.9 | 630.0 |
18 | 205 | -966 | 0 | -274.0 | -259.7 | 590.0 |
MCI | ||||||
24 | 513 | -2772 | 0 | -292.0 | -303.7 | 456.0 |
30 | 6 | -817 | 0 | -511.2 | -515.3 | -332.4 |
36 | 230 | -1482 | 0 | -430.0 | -456.8 | 548.0 |
48 | 232 | -2626 | 0 | -558.0 | -617.2 | 479.0 |
60 | 101 | -2185 | 0 | -649.0 | -713.7 | 240.0 |
66 | 18 | -1243 | 0 | -664.2 | -610.4 | 349.8 |
72 | 95 | -2525 | 0 | -729.0 | -801.2 | 394.0 |
78 | 28 | -1912 | 0 | -630.8 | -668.2 | 523.0 |
84 | 54 | -2063 | 0 | -641.1 | -712.0 | 409.3 |
90 | 28 | -2431 | 0 | -647.3 | -771.1 | 151.0 |
96 | 35 | -2848 | 0 | -868.0 | -900.3 | 440.9 |
102 | 21 | -2029 | 0 | -646.8 | -748.8 | 5.1 |
108 | 22 | -2928 | 0 | -679.4 | -886.3 | 304.5 |
114 | 8 | -2025 | 0 | -837.6 | -975.8 | -371.4 |
120 | 14 | -1508 | 0 | -954.4 | -914.8 | -199.0 |
126 | 6 | -1387 | 0 | -1282.1 | -1144.6 | -608.2 |
132 | 9 | -1130 | 0 | -444.1 | -609.5 | -162.3 |
144 | 6 | -1923 | 0 | -667.6 | -1020.2 | -419.6 |
3 | 92 | -685 | 0 | -36.0 | -30.1 | 927.0 |
6 | 191 | -1332 | 0 | -136.0 | -116.5 | 1865.0 |
12 | 199 | -1562 | 0 | -261.0 | -267.2 | 833.0 |
24 | 108 | -1109 | 0 | -416.0 | -435.1 | 1375.0 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
3 | 201 | -72848 | 0 | -2395 | -3018 | 35447 |
6 | 381 | -106897 | 0 | -4942 | -4579 | 101877 |
12 | 431 | -78206 | 0 | -7351 | -7196 | 51519 |
24 | 469 | -88405 | 0 | -13759 | -13156 | 475649 |
30 | 22 | -32766 | 0 | -12414 | -11120 | 11604 |
36 | 171 | -85200 | 0 | -20209 | -20227 | 41140 |
48 | 216 | -183387 | 0 | -28100 | -27806 | 47403 |
54 | 13 | -67270 | 0 | -33188 | -28837 | 20498 |
60 | 101 | -145445 | 0 | -40667 | -43638 | 44628 |
66 | 41 | -82351 | 0 | -38056 | -36903 | 39906 |
72 | 137 | -149221 | 0 | -47276 | -45401 | 64655 |
78 | 30 | -83931 | 0 | -39971 | -38238 | 25986 |
84 | 34 | -113695 | 0 | -16349 | -15831 | 56739 |
90 | 31 | -123532 | 0 | -50467 | -52030 | -5026 |
96 | 43 | -99261 | 0 | -30573 | -27419 | 41586 |
102 | 9 | -109557 | 0 | -60404 | -61424 | -8558 |
108 | 20 | -83236 | 0 | -31314 | -32128 | 24174 |
114 | 5 | -87489 | 0 | -52857 | -46819 | 12182 |
120 | 15 | -94523 | 0 | -45608 | -43946 | 12911 |
132 | 19 | -86393 | 0 | -27712 | -32188 | 14012 |
138 | 8 | -80558 | 0 | -49714 | -39430 | 31555 |
144 | 14 | -97927 | 0 | -43671 | -44896 | 11757 |
150 | 7 | -109584 | 0 | -44531 | -29903 | 43937 |
156 | 13 | -96677 | 0 | -54220 | -47150 | 36707 |
162 | 5 | -82452 | 0 | -18982 | -28415 | 1975 |
Dementia | ||||||
3 | 408 | -61742 | 0 | -1967 | -1456 | 40771 |
6 | 735 | -94640 | 0 | -4878 | -5163 | 92397 |
12 | 799 | -64433 | 0 | -9768 | -9923 | 55512 |
18 | 291 | -96551 | 0 | -17402 | -17710 | 57514 |
MCI | ||||||
24 | 606 | -318527 | 0 | -18034 | -19918 | 59818 |
30 | 7 | -54042 | 0 | -30132 | -32482 | -10890 |
36 | 295 | -143138 | 0 | -28545 | -30960 | 63734 |
48 | 248 | -160256 | 0 | -39111 | -41811 | 75934 |
60 | 117 | -189119 | 0 | -60540 | -64531 | 57796 |
66 | 22 | -87250 | 0 | -46729 | -42516 | 50524 |
72 | 125 | -228487 | 0 | -58662 | -61269 | 51610 |
78 | 29 | -131070 | 0 | -50056 | -51909 | -10480 |
84 | 60 | -140790 | 0 | -47730 | -43797 | 30939 |
90 | 34 | -129225 | 0 | -49424 | -54381 | 32702 |
96 | 40 | -92770 | 0 | -55517 | -50207 | 20738 |
102 | 24 | -89664 | 0 | -60276 | -60631 | -18168 |
108 | 27 | -152216 | 0 | -59304 | -62247 | 10736 |
114 | 9 | -86467 | 0 | -59096 | -55996 | 9118 |
120 | 16 | -95178 | 0 | -66478 | -53840 | 4340 |
126 | 8 | -164250 | 0 | -51270 | -57165 | 20119 |
132 | 10 | -87434 | 0 | -37822 | -41005 | -911 |
138 | 6 | -68077 | 0 | -30374 | -35819 | -22531 |
144 | 6 | -116380 | 0 | -41554 | -53921 | 4695 |
150 | 6 | -70254 | 0 | -35232 | -37728 | -7701 |
3 | 103 | -49206 | 0 | -5850 | -5798 | 22851 |
6 | 262 | -77681 | 0 | -9585 | -9763 | 80065 |
12 | 253 | -86270 | 0 | -18033 | -17425 | 62386 |
24 | 139 | -87554 | 0 | -33646 | -31828 | 32486 |
Month | N | Min. | NA. | Median | Mean | Max. |
---|---|---|---|---|---|---|
CN | ||||||
3 | 181 | -1224 | 0 | 6.0 | -51.49 | 694 |
6 | 331 | -1561 | 0 | -34.0 | -52.06 | 1535 |
12 | 368 | -1234 | 0 | -58.5 | -59.37 | 1304 |
24 | 400 | -1086 | 0 | -81.0 | -67.86 | 1364 |
30 | 22 | -769 | 0 | -40.0 | -82.86 | 639 |
36 | 139 | -1113 | 0 | -98.0 | -99.55 | 868 |
48 | 178 | -1491 | 0 | -142.5 | -94.52 | 1269 |
54 | 11 | -60 | 0 | 316.0 | 386.82 | 861 |
60 | 76 | -1744 | 0 | -143.0 | -185.05 | 1310 |
66 | 38 | -735 | 0 | 202.0 | 307.89 | 2169 |
72 | 112 | -1089 | 0 | -113.5 | -116.35 | 1081 |
78 | 27 | -780 | 0 | 250.0 | 243.85 | 1404 |
84 | 27 | -1218 | 0 | -7.0 | -80.70 | 817 |
90 | 28 | -1093 | 0 | 162.5 | 139.14 | 1689 |
96 | 39 | -1280 | 0 | 15.0 | -6.85 | 1213 |
102 | 8 | -1103 | 0 | 262.0 | 198.38 | 1547 |
108 | 16 | -1156 | 0 | -302.5 | -205.12 | 908 |
114 | 5 | -1620 | 0 | -247.0 | -428.80 | 234 |
120 | 14 | -973 | 0 | -502.0 | -303.93 | 1087 |
132 | 17 | -1797 | 0 | 119.0 | 96.41 | 1384 |
138 | 6 | -2089 | 0 | -464.0 | -519.33 | 546 |
144 | 12 | -644 | 0 | 2.0 | 49.25 | 975 |
156 | 12 | -1093 | 0 | -105.5 | -59.17 | 1238 |
Dementia | ||||||
3 | 350 | -1139 | 0 | -63.0 | -36.08 | 1178 |
6 | 585 | -1820 | 0 | -49.0 | -48.96 | 1230 |
12 | 623 | -1856 | 0 | -92.0 | -91.81 | 1461 |
18 | 205 | -1867 | 0 | -217.0 | -197.51 | 1797 |
MCI | ||||||
24 | 453 | -2163 | 0 | -170.0 | -179.00 | 897 |
30 | 6 | -555 | 0 | -308.0 | -346.83 | -110 |
36 | 212 | -2445 | 0 | -280.5 | -246.67 | 853 |
48 | 194 | -1970 | 0 | -243.5 | -320.97 | 967 |
60 | 91 | -1421 | 0 | -425.0 | -405.59 | 1647 |
66 | 19 | -1255 | 0 | -56.0 | 13.42 | 1084 |
72 | 92 | -1897 | 0 | -265.0 | -282.03 | 1218 |
78 | 27 | -1350 | 0 | 33.0 | -50.11 | 1238 |
84 | 50 | -1655 | 0 | 54.5 | -38.94 | 2068 |
90 | 28 | -1441 | 0 | 129.0 | -99.64 | 1003 |
96 | 28 | -1334 | 0 | 155.5 | 18.50 | 1186 |
102 | 21 | -1512 | 0 | 197.0 | 30.14 | 1237 |
108 | 25 | -1782 | 0 | 230.0 | -61.68 | 1141 |
114 | 8 | -944 | 0 | -199.5 | -51.50 | 1296 |
120 | 13 | -2237 | 0 | 346.0 | 218.31 | 1014 |
126 | 5 | -1898 | 0 | -748.0 | -562.80 | 1392 |
132 | 9 | -343 | 0 | 157.0 | 296.00 | 1060 |
144 | 6 | -586 | 0 | 557.5 | 485.50 | 1277 |
3 | 75 | -809 | 0 | 30.0 | 24.41 | 632 |
6 | 171 | -1681 | 0 | -67.0 | -27.35 | 1566 |
12 | 172 | -1437 | 0 | -160.0 | -145.38 | 1004 |
24 | 100 | -1224 | 0 | -246.0 | -261.47 | 489 |